- Sybil Isabel Dorsett (1923), the main personality.
- The names of these selves were also changed to ensure privacy. The book begins with a list of Sybil's "alters", together with the year in which each appeared to have dissociated from the central personality.
Wilbur writes that Sybil's multiple personality disorder was a result of the severe physical and sexual abuse she allegedly suffered at the hands of her mother, Hattie. Wilbur encouraged Sybil's various selves to communicate and reveal information about her life. Originally in treatment for social anxiety and memory loss, after extended therapy involving amobarbital and hypnosis interviews, Sybil manifests sixteen personalities. Mason is given the pseudonym "Sybil" by her therapist to protect her privacy.
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